Researchers Warn Molnupiravir Causes New Variants; mRNA Shots Contaminated with DNA Fragments

Medical scientists and researchers are increasingly challenging public health orthodoxies on FDA-approved COVID-19 treatments and vaccines.

A peer-reviewed paper published in Nature on Monday confirmed that Merck’s COVID-19 pill Molnupiravir causes viral mutations that can lead to new variants. Meanwhile, scientists have been raising the alarm about the Pfizer and Moderna Covid injections, warning that they are contaminated with tiny fragments of dangerous plasmid DNA that can cause genome changes that can “last for generations.”

These challenges to the public health establishment’s response to the coronavirus, come as health officials warn that COVID-19 cases are again on the rise and urge Americans to get boosted with the latest mRNA shots.

According to the new paper, the antiviral promoted by the CDC as a drug COVID patients should take “as soon as possible” has probably helped spur multiple variants since it was introduced in December of 2021.


“Molnupiravir, an antiviral medication that has been widely used against SARS-CoV-2, acts by inducing mutations in the virus genome during replication,” explained the study’s authors. They warned that patients who do not clear the virus after a few days of being on the antiviral medication could spread its mutated form to others.

Researchers analyzed 15 million COVID-19 genomes and found that new variants emerged in 2022 after Molnupiravir was introduced to many countries.  They also discovered that many of the novel sequences of the new variants were the same as those found in patients receiving the antiviral.

“A number of us, myself included, predicted from its mechanism of action that this would be the result when molnupiravir was approved and rolled out. Hence the ‘duh’ — it was obvious,” Dr. Harvey Risch, professor emeritus of epidemiology and senior research scientist at the Yale School of Public Health, told The Defender. “Obvious to everyone except the FDA [U.S. Food and Drug Administration] that is locked into pharma corruption.”

The authors of the study are affiliated with multiple research centers, including the Francis Crick Institute in London;  the Imperial College London; the Department of Bioinformatics, University of Cape Town; and NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, UK.

The researchers identified high rates of a specific mutation associated with molnupiravir in countries such as Australia, where retirement homes stocked up on the drug.

Most of the mutations linked to the drug have not been shown to be more serious or transmissible, however. The authors said most mutations weaken the virus by interfering with its self-replication ability.

Merck said in response to the study that the authors relied on “circumstantial associations” between observed variants and the drug rollout, and that the patients analyzed lacked “documented evidence of transmission.” Merck also claimed the mutations were “uncommon” and only associated with “sporadic cases.”

The FDA granted an emergency use authorization (EUA) to molnupiravir for use in certain populations in December 2021. The EUA was only narrowly approved (13-10) because even then, there were concerns within the FDA that the drug’s mutagenic effects could create new variants that evade immunity and prolong the COVID-19 pandemic.

Numerous medical scientists voiced their concerns about Molnupiravir in December of 2021, but their concerns were largely ignored.

Risch told Fox News at the time that molnupiravir “could create viral mutant strains all across the world. It’s a dangerous medication.”

Before the FDA approved the drug, William Haseltine, Ph.D., a former Harvard University virologist and author of “Variants! The Shape-Shifting Challenge of COVID-19,” warned about “supercharging new viral variants.”

“Molnupiravir works as an antiviral by tricking the virus into using the drug for replication, then inserting errors into the virus’ genetic code once replication is underway. When enough copying errors occur, the virus is essentially killed off, unable to replicate any further,” Haseltine wrote in Forbes.

“However, outside of the lab, as the drug is given to millions of people with active infections, this disadvantage [to viral replication] may quickly disappear as we would likely provide a prime selection environment to improve the fitness of the virus,” he added.

Paul Alexander, Ph.D. wrote in a December 2022 Substack post: “We [Dr. Geert Vanden Bossche, Michael Yeadon, Dr. Ramin Oskoui, Dr. Peter McCullough, Dr. Howard Tenenbaum, Risch, and others] told them, we warned them, but they would not stop.”

“Between this fraud failed mutagenic drug (on top of or in addition to the mutations driven by the COVID gene injection ‘vaccine’ itself in placing a spike antigen under population immune pressure) combined with Pfizer’s failed ‘rebound COVID’ Paxlovid, we are placing our people at great risk.”

Alexander argued that “we have a situation whereby COVID injections and pharma drugs are being given that will keep this pandemic going for 100 years.”

The drug’s inherent risks were so blatant, even the Washington Post raised concerns in a December 2021 article that noted Merck’s own research showed the virus could still be detected in a patient’s third day of treatment.  This meant the patient could be a “breeding ground for viable mutated viruses” presenting a “clear opportunity for mutant viruses to be transmitted to family members or caregivers.”

“As long as it is in use somewhere in the world, it could generate repeated cycles of new variants, with people desperately taking the drug to fight the new variants it spawns, creating a vicious positive feedback loop while causing more suffering and deaths,” The Post reported.

In January of 2022, India’s top medical research body, the Indian Council of Medical Research (ICMR), banned the drug’s use due to concerns over safety and mutagenicity. The Indian researchers blasted what they called “rampant and irrational use of the pill.”

“We had extensive discussions among national experts and reviewed whatever data was available from three trials – one on 1433 patients in the US; one which was prematurely terminated for business reasons and another that is ongoing,” Balram Bhargava, Director General of ICMR, said at the time. “The conclusion is that Molnupiravir has certain risks that warrant caution in its use. Experts present at the meeting opined that there is a rampant and irrational use of the pill. They said efforts should be made to restrict its use as known and unknown harms far outweigh its claimed benefit.”

The authors of the Nature study published a preprint study in January, “identifying the genetic signatures for the types of mutations caused by molnupiravir.”

Merck disputed the study, telling Bloomberg, “There is no evidence to indicate that any antiviral agent has contributed to the emergence of circulating variants.”

According to the Defender, “demand for Merck’s drug is down more than 83 percent for the quarter compared to last year when third-quarter sales reached more than $1 billion.”

Increasingly, scientists have been voicing concerns about the risky mRNA injections, as well.

Back in June, Microbiologist Kevin McKernan, a former researcher for the Massachusetts Institute of Technology Human Genome Project, announced that he had discovered simian virus 40 (SV40), a virus found in monkeys and humans, in the mRNA COVID-19 vaccines. SV40 has been linked to cancer in humans, including mesotheliomas, lymphomas and cancers of the brain and bone.

Cancer genomics expert Dr. Phillip Buckhaults, a former proponent of the mRNA shots who received the Pfizer Covid vax himself, confirmed the presence of DNA contaminants in the vaccines during a Senate hearing in South Carolina on September 15.

“I’m kind of alarmed about this DNA being in the vaccine – it’s different from RNA, because it can be permanent,” he said.

“There is a very real hazard,’ he said, that the contaminant DNA fragments will integrate with a person’s genome and become a ‘permanent fixture of the cell’ leading to autoimmune problems and cancers in some people who have had the vaccinations.” The doctor noted that these genome changes can “last for generations.”

Buckhaults said that the presence of high levels of contaminant DNA in the mRNA vaccines “may be causing some of the rare but serious side effects, like death from cardiac arrest.” He added, “I think this is a real serious regulatory oversight that happened at the federal level.”


Another expert panelist, Dr. Janci Lindsay, argued that the contamination of the DNA in the shots was not an accident, and had to be due to nefarious intentions.

“The SV40 sequences, they should not be there. They don’t need to be there to grow this in bacteria. I don’t think it’s an accident. They could have chosen another plasmid that did NOT have the SV40 sequences,” Lindsay said.

“If these sequences sit above an oncogene, and they are promiscuous, that means they are likely to integrate in places, more likely then other generic inserts. Then they can cause cancer,” she added. “There is something very unusual going on here.”

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About Debra Heine

Debra Heine is a conservative Catholic mom of six and longtime political pundit. She has written for several conservative news websites over the years, including Breitbart and PJ Media.

Photo: UKRAINE - 2021/04/27: In this photo illustration, silhouette of hands in medical gloves hold a medical syringe and a vial in front of Pfizer,Biontech,AstraZeneca,Moderna,Johnson & johnson,Novavax,Merck and Janssen logos. (Photo Illustration by Pavlo Gonchar/SOPA Images/LightRocket via Getty Images)