The only way to restore public trust in vaccination – which has taken a big hit since the lies attending the rollout of the COVID-19 vaccine – is to put a well-known vaccine skeptic in charge of the vaccine research agenda. The ideal person for this is Robert F. Kennedy Jr., who has been nominated to lead the Department of Health and Human Services.
At the same time, we must put rigorous scientists with a proven track record of evidence-based medicine in charge of determining the type of study designs to use. Two ideal scientists for this are Dr. Jay Bhattacharya and Dr. Marty Makary, who have been nominated to lead the NIH and FDA, respectively.
Vaccines are – along with antibiotics, anesthesia, and sanitation – one of the most significant health inventions in history. First conceived in 1774 by Benjamin Jesty, a farmer in Dorsetshire, England, the smallpox vaccine alone has saved millions of lives. Operation Warp Speed, which rapidly developed the COVID vaccines, saved many older Americans. Despite this, we have seen a sharp increase in general vaccine hesitancy. Vaccine scientists and public health officials who did not conduct properly randomized trials made false claims about vaccine efficacy and safety and established vaccine mandates for people who did not need the vaccines, sowing suspicion and damaging public trust in vaccination.
What went wrong? The purpose of the COVID vaccines was to reduce mortality and hospitalization, but the randomized trials were only designed to demonstrate short-term reduction in COVID symptoms, which is not of great public health importance. Since the placebo groups were promptly vaccinated after the emergency approval, they also failed to provide reliable information about adverse reactions. Despite these flaws, it was falsely claimed that vaccine-induced immunity is superior to natural infection-acquired immunity and that the vaccines would prevent infection and transmission.
Governments and universities then mandated the vaccines for people with superior natural immunity and for young people with very low mortality risk. These mandates were not only unscientific but with a limited vaccine supply, it was unethical to vaccinate low-mortality-risk people when the vaccines were needed by older high-risk people around the world.
Since government and pharmaceutical companies lied about the COVID vaccine, are they also lying about other vaccines? Skepticism has now spread to tried-and-true vaccines that are proven to work.
And there are real, unanswered vaccine safety questions. Seminal work from Denmark has shown that vaccines can have both positive and negative non-specific effects on non-targeted diseases, and that is something that must be explored in greater depth. Vaccine Safety Datalink (VSD) scientists studying asthma and aluminum-containing vaccines concluded that while their “findings do not constitute strong evidence for questioning the safety of aluminum in vaccines … additional examination of this hypothesis appears warranted.”
While VSD and other scientists should continue to do observational studies, we should also conduct randomized placebo-controlled vaccine trials, as RFK has advocated. Since we have herd immunity for many diseases, such as measles, trials can be ethically conducted by randomizing the age of vaccination to, for example, one versus three years old, while spreading the trial over a large geographical area so that the unvaccinated are not all living close to each other.
I am confident that most vaccines will continue to be found safe and effective. While some problems may be found, that is more likely to increase rather than decrease vaccine confidence. For instance, it was found that the measles-mumps-rubella-varicella (MMRV) vaccine causes excess febrile seizures in 12- to 23-month-old children. MMRV is now only given as a second dose to older children, while the younger kids get separate MMR and varicella vaccines, resulting in fewer vaccine-induced seizures that scare parents. Although safety studies were inconclusive, it was also wise to remove mercury from vaccines. Even if we end up with fewer vaccines in the recommended vaccine schedule, that’s not necessarily a terrible thing. Scandinavia has a very healthy population with fewer vaccines in their schedules.
We won’t restore vaccine confidence by preaching to the choir. After the COVID debacle, Kennedy’s stated goal is to return to evidence-based medicine free from conflicts of interest. Letting him do that is the only way that skeptics will trust vaccines again, and those of us who trust vaccines have no reason to be afraid of that.
Attempts by the public health and pharma establishments to derail the nominations of RFK, Bhattacharya, and Makary are the surest way to further increase vaccine hesitancy in America. The choice is stark. We cannot let lopsided “pro-vaccine scientists” who clamp their hands over their ears at the mildest questions do any more harm to vaccine confidence. As a pro-vaccine scientist, and in fact, the only person ever being fired by the CDC for being too pro-vaccine, the choice is clear in my mind. To restore vaccine confidence to previous levels, we must support the nominations of Kennedy, Bhattacharya, and Makary.
The author and I can agree on two things-- that Kennedy, Bhattacharya and Makary nominations should be confirmed and the vaccines were a major medical milestone. Beyond those points, I think we share little common ground.
The author states that the COVID jab saved many older Americans. Based on what evidence? Neither the numbers nor my personal observations support that claim. And, while the debate over vaccine safety gained massive momentum because of the messaging, policies and information manipulation surrounding mRNA gene therapy, vaccine skepticism has been on the rise for 20-30 years and with cause after Congress caved to threats from the pharmaceutical industry and removed most of the stipulations placed on vaccine manufacturing that made them safe for the vast majority of recipients.
The standard series of childhood vaccinations that are mandated today are significantly different in both scope and in composition from the ones I received as a child, which were safe, effective and underwent rigorous long-term testing prior to being widely employed. That has not been the case with reformulations of older vaccines and introductions of new ones – Gardasil is the one that comes to mind first-- that have been added since the mid-90s.
No one can reasonably argue that vaccines have had a tremendous impact on public health but the days of blind faith in what the experts recommend are over because it has been widely demonstrated that those experts are willing to lie to serve either agenda or profits over public health or safety. Until there is a return to the old standards for vaccine production and the FDA approval process, there will be skepticism.
Yes on Bhattacharya and Makary, no on RFK. Perhaps it was helpful to Trump to bring him on board for the campaign, but it’s time to shunt him aside. He’s unqualified and he’s all about big government. He’s also a global-warming extremist who could easily find a way to use the HHS position to implement destructive energy policies.